Overview

ImQuest BioSciences provides antiviral drug testing services to help our clients identify antiviral products that inhibit the replication of viruses in vitroex vivo and in vivo models. Our staff has decades of experience providing quality, efficient and cost-effective services.

Our antiviral drug testing services are available for the evaluation of small molecules, natural products, immune modulators, biologics and therapeutic antibodies. These assays provide necessary support from initial discovery, structure-activity relationship evaluation, lead identification and IND-directed preclinical development.

Don’t see the assay you are looking for?  Contact our technical team.  We can explore assay transfer or internalization from a pre-developed or published method and perform a feasibility review.

Technical Capabilities

  • In vitro screening: determination of efficacy and toxicity in cell lines and primary cells
  • Secondary range of action assays
    • Evaluation in human cell types for host directed products
    • Drug-resistant virus isolate evaluations and selection
    • Cell-to-cell transmission evaluation
    • Virucidal activity evaluation
    • Serum and serum protein binding effects
    • Varied time of drug addition and viral multiplicity of infection
    • Efficacy against DNA and RNA virus panels
  • Mechanism of action evaluations
  • Drug target validation (cell-based, molecular/biochemical and enzymatic assay endpoints)
  • Combination therapy evaluations
  • Drug resistant virus selection and characterization analysis
  • In vivo analysis of product efficacy and toxicity
  • Virus stock production services

Explore Virus Panels Click Here

Request a Scientific Consultation

We would love to hear more about your research and development needs. Contact us and we can coordinate a discussion with one of our technical directors to better understand your needs and develop a customized solution.

Can’t find what you are looking for? Reach out to us, we can help.

Explore Additional Services

The ImQuest scientific team has extensive expertise in the development of small molecules, natural products, biologics and vaccines for the treatment and prevention of infectious disease, cancer, and inflammatory disease. Explore our additional service offerings, or reach out to schedule a consultation.

Our Mission

Our goal is to help our clients accelerate their research and development efforts leading to the successful development of new products for the prevention and treatment of human disease. We have a very specific mission; accelerate your research and development plans and provide robust data in support of your projects.