Primary Cell Toxicity Panel

ImQuest BioSciences offers a panel of primary cell based in vitro toxicity assays to evaluate the off-target effects of pharmaceutical products. These assays predict the toxicity of compounds and can identify potential safety and drug development problems prior to in vivo safety and toxicology evaluations.

Cytotoxicity evaluations are performed with cell types representative of the major functional organ and immune systems and can be utilized to assess the effects of test compounds on cell viability, cell proliferation and macromolecular synthesis.

Other primary cell types are available upon request and may require pilot assays to determine optimal viability endpoint. Cell line based screening is also available.

Validated Primary Cell Toxicity Panel

  • Peripheral blood mononuclear cells (PBMCs)
  • Monocyte-macrophages
  • Dendritic cells
  • Bone marrow progenitor cells
  • Primary hepatocytes
  • Induced pluripotent stem cell (iPS)
  • Cardiomyocytes
  • iPS neurons
  • Renal proximal tubule cells (RPTEC)

Cytotocity and Mechanism Assays Click Here

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Explore Additional Services

The ImQuest scientific team has extensive expertise in the development of small molecules, natural products, biologics and vaccines for the treatment and prevention of infectious disease, cancer, and inflammatory disease. Explore our additional service offerings, or reach out to schedule a consultation.

Our Mission

Our goal is to help our clients accelerate their research and development efforts leading to the successful development of new products for the prevention and treatment of human disease. We have a very specific mission; accelerate your research and development plans and provide robust data in support of your projects.