ImQuest’s toxicology services quantify the toxicity and off-target effects of potential drug products through a variety of in vitro and ex vivo assays utilizing cell lines and primary cells. Assays enable early identification of off target effects to inform IND-directed development of novel test articles.
Our services are available for the evaluation of small molecules, natural products, immune modulators, biologics and therapeutic antibodies. A wide variety of primary cell types available.
Customized assay design, endpoint modification, and internalization and validation of pre-developed or published methods are available. Contact us to discuss in vitro toxicology assay needs not specifically listed.
In vitro cytotoxicity in primary cell panels:
In vitro cytotoxicity in established cell lines:
In vitro cytotoxicity endpoints:
- Cell viability
- Macromolecular synthesis
- Membrane integrity
- Cell proliferation
- Oxidative stress
- Immunotoxicity Evaluations
- Flow Cytometric Assays
- In Vitro Drug Permeability Evaluation
- In Vitro Metabolism
- Drug-drug interactions
- Genomic Toxicology Analysis
- Pharmacokinetics and pharmacodynamics
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We would love to hear more about your research and development needs. Contact us and we can coordinate a discussion with one of our technical directors to better understand your needs and develop a customized solution.
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Explore Additional Services
The ImQuest scientific team has extensive expertise in the development of small molecules, natural products, biologics and vaccines for the treatment and prevention of infectious disease, cancer, and inflammatory disease. Explore our additional service offerings, or reach out to schedule a consultation.
Our goal is to help our clients accelerate their research and development efforts leading to the successful development of new products for the prevention and treatment of human disease. We have a very specific mission; accelerate your research and development plans and provide robust data in support of your projects.