Outsourced R&D Support

Our biological technical services are an integrated component of our research programs and are also available as stand-alone service components of our infectious disease, cancer, tissue culture, cell biology, molecular biology, biochemistry and immunology research and development programs. Save time and resources by outsourcing your basic and translational research and development needs.

Customized assay design, endpoint modification, and internalization and validation of pre-developed or published methods is available.  Contact us to discuss assay needs not specifically listed.

Technical Capabilities

Molecular Biology Laboratory Services

Our expert staff has years of experience in the fields of molecular biology, biochemistry, genetics, virology and microbiology and are capable of handling both routine tasks and custom research and development projects in order to provide a broad range of core molecular biology services, including:

  • Virus production and genotypic characterization
  • Sequencing and identification of antimicrobial target genes
  • Quantitative real time PCR
  • Single Nucleotide Polymorphism (SNP) detection
  • Cloning and sequencing of recombinant plasmids
  • Gene expression analysis
  • Recombinant protein expression and purification
  • Protein-protein and protein-nucleic acid interactions
  • Microbial resistance characterization
  • Novel target identification and assay development
  • Analysis of pathogen-host interactions

Tissue Culture, Cellular Biology and Repository Services

Utilizing over 20 years of in vitro cell and tissue culture experience, ImQuest BioSciences provides technical services in the following areas:

  • Preparation and maintenance of cell lines or primary cell cultures
  • Organ cultures
  • Virus stock production
  • Bacteria stock production
  • Cell and virus repository
  • Baculovirus expression systems
  • Procaryotic expression systems
  • Immunofluorescent microscopy

ELISA, Immunology and Flow Cytometry Services

  • ELISA and Immunoassay development
    • Antigen specific ELISAs
    • ELISA method development, validation and transfer
    • ELISA kit validation
  • Multicolor Flow Cytometry:
    • Multi-parameter flow cytometry analysis up to 8 parameters
    • Custom assay development and validation
    • Immunophenotyping
    • Cell Exhaustion and Activation Marker Analysis
    • Apoptosis and Necrosis Assays
    • Intracellular cytokine assays (ICS)
    • Cell Viability Assays
    • Proliferation assays in response to specific peptide antigens or mitogens (Con A, PHA, etc.)
    • Intracellular Calcium Flux Assays
  • Antigen-specific ELIspot assays
  • Tissue cross-reactivity assays and immunohistochemistry
  • Neutralizing antibody and other cell based assays
  • Biomarker discovery and validation
  • Determination of gene expression patterns by real time qPCR
  • PBMC isolation and immunogenicity screening
  • Analysis of clinical samples to determine the immune response evoked by the treatment

Biochemistry and Enzymology Laboratory Services

Full service laboratories for biochemistry and enzymology. State-of-the-art instrumentation for analysis of enzyme activity and macromolecular interactions. Expertise in early to late-stage preclinical protein drug development from protein expression and optimization to purification protocol design. With a core biochemistry and immunology laboratory facility, we are capable of providing services covering the following functions.

    • Protein production
    • Protein analytical and bioanalytical services
    • Protein therapeutic support
    • Enzymology
    • Standard and customized antiviral enzyme assays
    • Host cell polymerase assays
    • Assay development and optimization
    • Drug development support

Molecular Biology Services Click Here

Request a Scientific Consultation

We would love to hear more about your research and development needs. Contact us and we can coordinate a discussion with one of our technical directors to better understand your needs and develop a customized solution.

Can’t find what you are looking for? Reach out to us, we can help.

Explore Additional Services

The ImQuest scientific team has extensive expertise in the development of small molecules, natural products, biologics and vaccines for the treatment and prevention of infectious disease, cancer, and inflammatory disease. Explore our additional service offerings, or reach out to schedule a consultation.

Our Mission

Our goal is to help our clients accelerate their research and development efforts leading to the successful development of new products for the prevention and treatment of human disease. We have a very specific mission; accelerate your research and development plans and provide robust data in support of your projects.