ImQuest BioSciences provides antiviral drug testing services to help our clients identify antiviral products that inhibit the replication of viruses in vitro, ex vivo and in vivo models. Our staff has decades of experience providing quality, efficient and cost-effective services.

Our antiviral drug testing services are available for the evaluation of small molecules, natural products, immune modulators, biologics and therapeutic antibodies. These assays provide necessary support from initial discovery, structure-activity relationship evaluation, lead identification and IND-directed preclinical development.

Don’t see the assay you are looking for?  Contact our technical team.  We can explore assay transfer or internalization from a pre-developed or published method and perform a feasibility review.

• In vitro screening: determination of efficacy and toxicity in cell lines and primary cells
• Secondary range of action assays
  • Evaluation in human cell types for host directed products
  • Drug-resistant virus isolate evaluations and selection
  • Cell-to-cell transmission evaluation
  • Virucidal activity evaluation
  • Serum and serum protein binding effects
  • Varied time of drug addition and viral multiplicity of infection
  • Efficacy against DNA and RNA virus panels
• Mechanism of action evaluations
• Drug target validation (cell-based, molecular/biochemical and enzymatic assay endpoints)
• Combination therapy evaluations
• Drug resistant virus selection and characterization analysis
• In vivo analysis of product efficacy and toxicity
• Virus stock production services