Resource Library

Publications Abstracts White Papers

Publications

Vaginal deployment and tenofovir delivery by microbicide gels.

Gao Y, Yuan A, Chuchuen O, HAM AS, Yanf KH, Katz DF. 2015

Microbicide, Retrovirology

Current and emerging formulation strategies for the effective transdermal delivery of HIV inhibitors.

HAM AS, Buckheit RW. 2015

Forumulation, Microbicide, Pharmaceutical

In vitro and ex vivo evaluations on transdermal delivery of the HIV inhibitor IQP-0410.

HAM AS, Lustig WP, Boczar AM, Yang L, Buckheit KW, Buckheit RW. 2013

Forumulation, Microbicide, Pharmaceutical

The rational design and development of a dual chamber vaginal/rectal microbicide gel formulation for HIV prevention.

HAM AS, Nugent ST, Peters JJ, Katz DF, Shelter C, Dezzutti CS, Boczar AD, Buckheit KW, Buckheit RW. 2015

Microbicide

Current Concepts for the IND-Directed Development of Microbicide Products to Prevent the Sexual Transmission of HIV.

Buckheit TK, Furlan-Freguia C, HAM AS, Buckheit RW Jr. 2015

Microbicide

Abstracts

Pharmacokinetic and Pharmacodynamic Evaluation of IQP-0528 Quick-Dissolving Films in Macaques as an HIV Microbicide

2015 AAPS Meeting Abstract

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Formulation Development of the DuoGel: A Dual Chamber Vaginal/Rectal Anti-HIV Gel

Anthony Ham, William Lustig, Sean T. Nugent, Jennifer Peters, David Katz, Cory Shelter, Charlene Dezzutti, Ashlee Boczar, Karen W. Buckheit, and Robert W. Buckheit, Jr., American Association of Pharmaceutical Science, 2013

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In Vitro Evaluation of the HIV Therapeutic IQP-0410 Through Transdermal Film Delivery

Anthony S. Ham, William P. Lustig, Ashlee D. Boczar, Karen W. Buckheit, and Robert W. Buckheit, Jr., International Conference on Antiviral Research, 2013

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The Importance and Role of Formulation in Antiviral Drug Development Programs

Anthony Ham, Invited Presentation at International Conference on Antiviral Research, 2013

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Defining the Concentration of an Antiviral Agent Required to Suppress Virus Infection, Replication and Transmission

Karen W. Buckheit, Ashlee D. Boczar, Caitlin A. Buchholz and Robert W. Buckheit, Jr., International Conference on Antiviral Research, 2013

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Evaluation of Candidate Topical Microbicides in Pharmacokinetic and Pharmacodynamic In Vitro Models to Predict the Necessary Concentration Required to Prevent HIV Infection

Mansoora Khaliq, Karen W. Buckheit, Charlene S. Dezzutti and Robert W. Buckheit, Jr., International Conference on Antiviral Research, 2013

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Development of Influenza Virus Inhibitors with a High Genetic Barrier to Resistance

Tracy L. Hartman and Robert W. Buckheit, Jr., International Conference for Antiviral Research, 2013

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Evolution of Pyrimidinedione HIV Therapeutic Agents with Improved Solubility and Metabolic Stability

Robert W. Buckheit, Jr., International Conference on Antiviral Research, 2013

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The ImQuestSUCCESS Drug Development Platform: Enhancing Successful Drug Development Opportunities

Robert W. Buckheit, Jr., Karen W. Buckheit, Christian Furlan-Frequia, Anthony Ham, Tracy Hartman, Mansoora Khaliq and Todd B. Parsley, International Conference on Antiviral Research, 2013

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IND-Directed Development of Dual-Acting Pyrimidinediones IQP-0410 and IQP-0528: Enhancement of Solubility and Metabolic Stability

T.L. Hartman, L. Yang, K.W. Buckheit and R.W. Buckheit, Jr., International Conference on Antiviral Research, 2012.

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A Nanoparticle Based Targeted Delivery System for a Combination Microbicide Product

Anthony Ham, Brady Zarket, William Lustig, Karen W. Buckheit, and Robert W. Buckheit, Jr., American Association of Pharmaceutical Science, 2012

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Development of Next Generation Pyrimidinedione Inhibitors of HIV

T.L. Hartman, L. Yang and R.W. Buckheit, Jr., HIV-DART, 2010.

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Advanced Development of Dual-Acting Pyrimidinediones as Highly Potent Anti-HIV Therapeutic Drugs and Topical Microbicides

Robert W. Buckheit, Jr., HIV-DART, 2010

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White Papers

Biofilm Protocol Optimization for Pseudomonas aeruginosa

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In vitro Toxicology Cytotoxicity and Mechanism

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Biofilm Protocol Optimization with Gram-Positive Cocci

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Hepatitis B Antiviral Drug Development: Multi-Parameter Screening Assay

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Antibiotic-Resistant Microbe Panel for the Evaluation of New Antimicrobial Agents

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HIV Antiviral Drug Development: Evaluation of Fullerene Poly-Aminocaproic Acid

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HIV Antiviral Drug Development: Evaluation of HIV Priming Complex Inhibitors

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In Vivo Mouse Models of Bacterial Infection: Neutropenic Thigh Model

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In Vivo Mouse Models of Bacterial Infection: Peritonitis-Sepsis Model of MRSA Infection

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Influenza Antiviral Drug Development: Polymerase Inhibition Assay

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Influenza Antiviral Drug Development: Evaluation of Antiviral Drug Combinations

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Influenza Antiviral Drug Development: Efficacy, Toxicity, Range and Mechanism of Action

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Formulation: Polymeric Delivery using Films and Patches

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