Publications

Vaginal deployment and tenofovir delivery by microbicide gels.

Gao Y, Yuan A, Chuchuen O, HAM AS, Yanf KH, Katz DF. 2015

Microbicide Retrovirology

Current and emerging formulation strategies for the effective transdermal delivery of HIV inhibitors.

HAM AS, Buckheit RW. 2015

Forumulation Microbicide Pharmaceutical

In vitro and ex vivo evaluations on transdermal delivery of the HIV inhibitor IQP-0410.

HAM AS, Lustig WP, Boczar AM, Yang L, Buckheit KW, Buckheit RW. 2013

Forumulation Microbicide Pharmaceutical

The rational design and development of a dual chamber vaginal/rectal microbicide gel formulation for HIV prevention.

HAM AS, Nugent ST, Peters JJ, Katz DF, Shelter C, Dezzutti CS, Boczar AD, Buckheit KW, Buckheit RW. 2015

Microbicide

Current Concepts for the IND-Directed Development of Microbicide Products to Prevent the Sexual Transmission of HIV.

Buckheit TK, Furlan-Freguia C, HAM AS, Buckheit RW Jr. 2015

Microbicide

Pharmacokinetic and pharmacodynamic evaluation following vaginal application of DuoGel™ containing the NNRTI IQP-0528 in rhesus macaques

Pereira L, Mesquita P, HAM AS, Singletary T, Deyounks F, Martin A, McNicholl J, Watson-Buckheit K, Buckheit RW Jr., Smith J. 2015

Microbicide

Griffithsin tandemers: flexible and potent lectin inhibitors of the human immunodeficiency virus.

Moulaei, T., Alexandre, K. B., Shenoy, S. R., Meyerson, J. R., Krumpe, L. R., Constantine, B., Wilson, J., Buckheit, R. W., Jr. McMahon, J. B., Subramaniam, S., Wlodawer, A., O'Keefe, B. R. , 2015

Antiviral

Meaning-making matters in product design: users' sensory perceptions and experience evaluations of long-acting vaginal gels and intravaginal rings.

Rosen, R. K., van den Berg, J. J., Vargas, S. E., Senocak, N., Shaw, J. G., Buckheit, R. W., Jr., Smith, K. A., Guthrie, K. M., 2015

Microbicide

Current Concepts for the IND-Directed Development of Microbicide Products to Prevent the Sexual Transmission of HIV.

Buckheit, K. W., Furlan-Freguia, C., Ham, A. S., Buckheit, R. W., Jr. , 2015

Microbicide

The Promise of Intravaginal Rings for Prevention: User Perceptions of Biomechanical Properties and Implications for Prevention Product Development.

Morrow Guthrie, K., Vargas, S., Shaw, J. G., Rosen, R. K., van den Berg, J. J., Kiser, P. F., Buckheit, K., Bregman, D., Thompson, L., Jensen, K., Johnson, T., Buckheit, R. W., 2015

Microbicide

Engineering soya bean seeds as a scalable platform to produce cyanovirin-N, a non-ARV microbicide against HIV.

O'Keefe, B. R., Murad, A. M., Vianna, G. R., Ramessar, K., Saucedo, C. J., Wilson, J., Buckheit, K. W., da Cunha, N. B. Araujo, A. C., Lacorte, C. C., Madeira, L., McMahon, J. B., Rech, E. L., 2015

Microbicide

An Intravaginal Ring for the Simultaneous Delivery of an HIV-1 Maturation Inhibitor and Reverse-Transcriptase Inhibitor for Prophylaxis of HIV Transmission.

Ugaonkar, S. R., Clark, J. T., English, L. B., Johnson, T. J., Buckheit, K. W., Bahde, R. J., Appella, D. H., Buckheit, R. W., Jr., and Kiser, P. F. , 2015

Forumulation

Pharmacokinetic and pharmacodynamic evaluation following vaginal application of IQB3002, a dual chamber microbicide gel containing the NNRTI IQP-0528 in rhesus macaques.

Pereira, L. E., Mesquita, P. M., Ham, A., Singletary, T., Deyounks, F., Martin, A., McNicholl, J., Buckheit, K. W., Buckheit, R. W., Jr., Smith, J. M. 2015

Microbicide

Novel preclinical models of topical PrEP and pharmacodynamics provide rationale for sutained intravaginal ring delivery of microbicide combinations.

Mesquita, P.M., Srinivasan, P., Johnson, T.J., Rastogi, R., Evans-Strickfaden, T., Kay, M.S., Buckheit, K.W., Buckheit, R.W., Jr., Smith, J.M., Kiser, P.F. and Herold, B.C., 2013

Microbicide

In vitro and ex vivo evaluations of transdermal delivery of the HIV inhibitor IQP-0410.

Ham, A.S., Lustig, W., Yang, L., Boczar, A., Buckheit, K.W., and Buckheit, R.W., Jr., 2013.

Forumulation

The Continuing Evolution of HIV Therapy: Identification and Development of Novel Antiretroviral Agents Targeting Viral and Cellular Targets

T.L. Hartman and R.W. Buckheit Jr., Molecular Biology International, 2012.

Anti-Infective

Selection and characterization of viruses resistant to the dual-acting pyrimidinedione entry and nonnucleoside reverse transcriptase inhibitor IQP-0410.

Buckheit, R.W., Jr., Buckheit, K.W., Sturdevant-Buckheit, C., and Buckheit, R.W., III., 2013.

Antiviral

Development of a combination microbicide gel formulation containing IQP-0528 and tenofovir for the prevention of HIV infection.

Ham, A.S., Ugaonkar, S.R., Shi, D., Buckheit, K.W., Lakougna, H., Nagaraja, U., Gwozdz, G., Goldman, L., Kiser, P.F. and Buckheit, R.W., Jr., 2012.

Pharmaceutical

Safe and sustained vaginal delivery of pyrimidinedione HIV-1 inhibitors from polyurethane rings.

Johnson, T., Srinivasan, P., Albright, T., Buckheit, K.W., Rabe, L., Martin, A., Otten, R., McNicholl, J., Buckheit, R.W., Jr., Smith, J. and Kiser, P. 56:1291-1299. 2012.

Microbicide

Safety and efficacy of tenofovir / IQP-0528 combination gels - a dual compartment microbicide for HIV-1 prevention.

Dezzutti, C.S., Shetler, C., Mahalingham, A., Ugaonkar, S.R., Gwozdz, G., Buckheit, K.W. and Buckheit, R.W., Jr., 2012.

Antiviral

Synthesis and anti-HIV activities of symmetrical dicarboxylate esters of dinucleotide reverse transcriptase inhibitors.

Agarwal, H.K., Buckheit, K.W., Buckheit, R.W., Jr. and Parang, K., 22: 5451-5454. 2012.

Vaginal film drug delivery of the pyrimidinedione IQP-0528 for the prevention of HIV infection.

Ham AS, Rohan LC, Boczar A, Yang L, W Buckheit K, Buckheit RW Jr. Pharm Res. 2012 Jul;29(7):1897-907.

Forumulation

The Continuing Evolution of HIV-1 Therapy: Identification and Development of Novel Antiretroviral Agents Targeting Viral and Cellular Targets.

Hartman, T.L. and Buckheit, R.W., Jr., doi:10.1155/2012/401965, Molecular Biology International, vol. 2012, Article ID 401965., 17 pages, 2012.

Factors Important to the Prioritization and Development of Successful Topical Microbicides for HIV-1

Buckheit, K.W. and Buckheit, R.W., Jr., doi:10.1155/2012/781305, Molecular Biology International, vol. 2012, Article ID 781305, 12 pages, 2012.

Microbicide

Development of a combination microbicide gel formulation containing IQP-0528 and tenefovir for the prevention of HIV infection.

Ham AS, Ugaonkar SR, Shi L, Buckheit KW, Lakougna H, Nagaraja U, Gwozdz G, Goldman L, Kiser PF, Buckheit RW Jr. J Pharm Sci. 2012 Apr;101(4):1423-35.

Forumulation

De novo design of antiviral and antibacterial peptides with varying loop structures.

Wang, G., Buckheit, K.W., Mishra, B., Lushnikova, T. and Buckheit, R.W., Jr., J. AIDS Clinic Res. S2:003. Doi: 10.4172/2156-6113. 2011.

Antiviral

Identification of novel human immunodeficiency virus type 1 inhibitory peptides based on the antimicrobial peptide database.

Wang, G., Watson, K.M., Peterkofsky, A. and Buckheit, R.W., Jr., 54: 1343-1346. 2010.

Microbicide

Antiviral interactions of highly potent 2,4 (1H, 3H)-pyrimidinedione congeners and other anti-HIV agents.

Hartman, T.L., Yang, L., and Buckheit, R.W., Jr., 92: 505-508. 2011.

Antiviral Interactions of Combinations of Highly Potent 2,4 (1H, 3H)-Pyrimidinedione Congeners and Other Anti-HIV Agents

T.L. Hartman, L. Yang and R.W. Buckheit, Jr., Antiviral Research, 2011. 92: p.505-8.

Anti-Infective

Development of dual-acting pyrimidinediones as novel and highly potent topical anti-HIV microbicides.

Buckheit, K.W., Yang, L. and Buckheit, R.W., Jr., 55: 5243-5254. 2011.

Microbicide

Enzymatic triggered release of the HIV-1 entry inhibitor from prostate specific antigen degradable microparticles.

Enzymatic triggered release of the HIV-1 entry inhibitor from prostate specific antigen degradable microparticles.

Pharmaceutical

Vaginal microbicide gel for delivery of IQP-0528, a pyrimidinedione analog with a dual mechanism of action against HIV-1.

Mahalingham, A., Simmons, A.P., Ugaonkar, S.R., Watson, K.M., Dezzutti, C.S., Rohan, L.C., Buckheit, R.W., Jr. and Kiser, P.F., 55: 1650-1660. 2011.

Microbicide

An Investigation of Phenylthiazole Antiflaviviral Agents.

Mayhoub A.S., Khaliq M., Botting C, Li Z., Kuhn RJ., and Cushman M. 2011. Biorganic & Medicinal Chemistry. 2011 Jun 15; 19(12): 3845-54

Anti-Infective

Design, Synthesis, and Biological Evaluation of Thiazoles Targeting Flavivirus Envelope Protein.

Mayhoub A.S., Khaliq M., Kuhn RJ., and Cushman M. Journal of Medicinal Chemistry. 2011 Mar 24; 54(6): 1704-14

Anti-Infective

Binaphthyl-based dicationic peptoids with therapeutic potential.

Bremner, J.B., Keller, P.A., Pyne, S.G., Boyle, T.P., Brkic, Z., David, D.M., Garas, A., Morgan, J., Rbertson, M., Somphol, K., Miller, M.H., Howe, A.S., Ambrose, P., Bhavnani, S., Fritsche, T.R., Biedenbach, D.J., Jones, R.N., Buckheit, R.W., Jr., Watson, K.M., Baylis, D., Coates, J.A., Deadman, J., Jeevarajah, D., McCracken, A. and Rhodes, D.I., 49: 537-540. 2010.

Development of hexadecyloxypropyl tenofovir (CMX 157) for the treatment of infection caused by wild type and nucleoside/nucleotide-resistant HIV.

Lanier, E.R., Ptak, R.G., Lampert, B.M., Keilholz, L., Hartman, T., Buckheit, R.W., Jr., Mankowski, M.K., Osterling, M.C., Almond, M.R., Painter, G.R., Antimicrob Agents Chemother, 54:2901-2909. 2010.

Microbicide

Inhibition of human immunodeficiency virus type 1 by triciribine involves the accessory protein Nef.

Ptak, R.G., Gentry, B.G., Hartman, T.L., Watson, K.M., Osterling, M.C., Buckheit, R.W., Jr., Townsend, L.B. and Drach, J.C., 54: 1512-1519. 2010.

Microbicide

Development of gfstopical microbicides to prevent the sexual transmission of HIV.

Buckheit, R.W., Jr., Watson, K.M, Morrow, K. and Ham, A., Antiviral Res. 85: 142-158. 2010.

Microbicide

Multivalent binding oligomers inhibit HIV Tat-Tar interaction critical for viral replication.

Multivalent binding oligomers inhibit HIV Tat-Tar interaction critical for viral replication.

Antiviral

Inhibition of Human Immunodeficiency Virus Type 1 by Triciribine Involves the Accessory Protein Nef.

R.G. Ptak, B.G. Gentry, T.L. Hartman, K.M. Watson, M.C. Osterling, R.W. Buckheit, Jr., L.B. Townsend, and J.C. Drach, Antimicrobical Agents and Chemotherapy, 2010. 54(4): p.1512-9.

Anti-Infective

Development of topical microbicides to prevent the sexual transmission of HIV

Buckheit RW, Watson KM, Morrow KM, Ham AS. Antiviral Research 2010 85(1):142-58.

Microbicide

Crystallographic study of a novel sub-nanomolar inhibitor provides insight on the binding interactions of alkenylydiarylmethanes with human immunodeficiency virus-1 (HIV-1) reverse transcriptase.

Cullen, M.D., Ho, W.C., Bauman, J.D., Das, K., Arnold, E., Hartman, T., Watson, K., Buckheit, R.W., Jr., Pannecouque, C., DeClerq, E. and Cushman, M., J. Med. Chem. 52: 6467-6473. 2009.

1-Benzoyl Derivatives of 5-(Arylamino)uracils as anti-HIV-1 and Anti-EBV agents.

Novikov, M.S., Buckheit, R.W., Jr., Temburnikar, K., Khandazhinskaya, A.L., Ivanov, A.V., Seley-Radtke, K.L., Bioorg Med Chem 18: 8310-8314. 2010.

Antiviral

Synthesis of alkenyldiarylmethanes (ADAMs) containing the benzo[d]isoxazole and oxazolidin-2-one rings, a new series of potent non-nucleoside HIV-1 reverse transcriptase inhibitors.

Deng, B-L., Zhao, Y., Hartman, T.L., Watson, K., Buckheit, R.W., Jr., Pannecouque, C., De Clercq, E. and Cushman, M. - Eur. J. Med. Chem. 44: 1210-1214. 2009

Review: Novel targets of HIV therapy.

Greene, W.C., Debyser, Z., Ikeda, Y., Freed, E.O., Stephens, E., Yonemoto, W., Buckheit, R.W., Jr., Este, J.A., and Cihlar, T. - Antiviral Research. 80: 251-265. 2008.

Antiviral

Anti-HIV-1 activity of antimicrobial peptides derived from human and bovine cathelicidins.

Wang, G., Watson, K.M., and Buckheit, R.W., Jr. - Antimicrob. Agents Chemother. 52:3438-3440. 2008.

Microbicide

Comparative evaluation of virus tansmission inhibition by dual-acting pyrimidinedione microbicides using the microbicide transmission and sterilization assay (MTSA). Electronic publication ahead of print.

Watson, K.M., Buckheit, C.E. and Buckheit, R.W., Jr. - Antimicrob. Agents Chemother. 2008.

Microbicide

Investigation of the alkenyldiarylmethane non-nucleoside reverse transcriptase inhibitors as potential cAMP phosphodiesterase-4B2 inhibitors.

Cullen, M.D., York-Fong, C., Houslay, M., Hartman, T.L., Watson, K.M., Buckheit, R.W., Jr., Pannecouque, C., DeClercq, E. and Cushman, M. - Bioorg. Med. Chemistry Letters. 18: 1530-1533. 2008.

Development of a comprehensive human immunodeficiency virus type-1 screening algorithm for discovery and preclinical testing of topical microbicides.

Lackman-Smith, C., Osterling, C., Luckenbaugh, K., Mankowski, M., Snyder, B., Lewis, G., Paull, J., Profy, A., Ptak, R., Buckheit, R.W., Jr., Watson, K.M., Cummins, J.E. and Sanders-Beer, B.E. - Antimicrob. Agents Chemother. 52: 1768-1781. 2008.

Microbicide

Inhibition of tubulin polymerization by select alkenyldiarylmethanes.

Cullen, M.D., Hamel, E., Hartman, T.L., Watson, K.M., Buckheit, R.W., Jr., Pannecouque, C., De Clercq, E. and Cushman, M. - Bioorg. Med. Chemistry 18:469-473. 2008.

Comparative evaluation of the inhibitory activity of a series of pyrimidinedione congeners which inhibit both HIV-1 and HIV-2.

Buckheit, R.W., Jr., Hartman, T.L., Watson, K.M., Chung, S-G. and Cho, E-H. - Antimicrobial Agents Chemother. 52: 225-236. 2008.

Microbicide

Synthesis and biological evaluation of alkenyldiarylmethane HIV-1 non-nucleoside reverse transcriptase inhibitors that possess increased hydrolytic stability.

Cullen, M., Deng, B.L., Hartman, T., Watson, K. Buckheit, R.W., Jr., Pannecouque, C., DeClercq, E. and Cushman, M. - J. Med. Chem. 50:4854-4867. 2007.

Synthesis and Anti-HIV Activity of New Metabolically Stable Alkenyldiarylmethane Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) Incorporating N-Methoxy Imidoyl Halide and 1,2,4-Oxadiazole Systems.

Sakamoto, T., Cullen, MD, Hartman, TL, Watson, KM, Buckheit, RW, Jr., Pannecouque, C. and De Clercq, E. and Cushman, M. - J. Med. Chem. 50: 3314-3321. 2007.

Antiviral

The structure-activity relationships of 2,4 (1H, 3H)-pyrimidinedione derivatives as potent human immunodeficiency virus type-1 and type-2 inhibitors.

Buckheit, R.W., Jr., Hartman, T.L., Watson, K., Kwon, H-S., Lee, S-H., Lee, J-W., Kang, D-W., Chung, S-G., Cho, E-H. - Antiviral Chemistry and Chemotherapy, 18: 259-275. 2007.

Antiviral

Synthesis, biological activity, and crystal structure of potent nonnucleoside inhibitors of HIV-1 reverse transcriptase that retain activity against mutant forms of the enzyme.

Morningstar, M.L., Roth, T., Farnsworth, D.W., Kroeger-Smith, M., Watson, K., Buckheit, R.W., Jr., Das, K., Zhang, W., Arnold, E., Julias, J.G., Hughes, S.H. and Michejda, C.J. - J. Med. Chem. 50: 4003-4015. 2007.

Carrageenan/MIV-150 (PC-815), a combination microbicide.

Fernández-Romero, JA, Thorn, M, Turville, SG, Titchen, K, Sudol, K., Li, J., Maguire, RM, Buckheit R.W., Jr, Hartman, T.L., and Phillips, D.M. - Sex Transm. Dis. 34: 9-14. 2007.

Microbicide

Total synthesis of Anibamine, a novel natural product as a chemokine receptor CCR5 antagonist.

Li, G., Watson, K., Buckheit, R.W. and Zhang, Y. - Organic Letters. 9: 2043-2046. 2007.

Replacement of the metabolically labile methyl esters in the alkenyldiarylmethane series of non-nucleoside reverse transcriptase inhibitors with isoxazolone, oxazolone, or cyano substituents.

Deng, B.L., Hartman, T.L., Buckheit, R.W., Jr., Pannecouque, C., DeClercq, E. and Cushman, M. - J. Med.Chem. 49: 5316-5323. 2006.

Synthesis and anti-HIV-1 activity of 1-[2-(2-benzyl-4-methylphenoxy)ethyl]uracil derivatives.

Novikov M.S., Orlova Yu.A., Ozerov A.A., Hartman T., Buckheit R.W. - Bulletin of Volgograd Scientific Centre of Russian Academy of Medical Science. 2006. - No. 4. - P. 11-15.

Antiviral

Synthesis of novel non-symmetrical 1,3-disubstituted uracil derivatives and investigation of their anti-HIV-1 activity in vitro.

Novikov M.S., Orlova Yu.A., Solodunova A.A., Ozerov A.A., Hartman T., Buckheit R.W. - Bulletin of Volgograd Scientific Centre of Russian Academy of Medical Science. 2006. - No. 4. - P. 6-8.

Antiviral

In vitro preclinical testing of nonoxynol-9 as potential anti-human immunodeficiency virus microbicide: a retrospective analysis of results from five laboratories.

Beer, B.E., Doncel, G.F., Krebs, F.C., Shattock, R., Fletcher, P., Buckheit, R.W., Jr., Watson, K., Dezzutti, C.S., Cummins, J.E., Bromley, E., Richardson-Harman, N., Pallansch, L., Lackman-Smith, C., Ostreling, C., Mankowski, M., Miller, S.R., Catalone, B.J., Welsh, P.A., Howett, M.K., Wigdahl, B., Turpin, J.A. and Reichelderfer, P. - Antimicrob. Agents Chemother. 50:713-723. 2006.

Antiviral Microbicide

In vitro and in vivo characterization of a potential universal placebo designed for use in vaginal microbicide clinical trials.

Tien, D., Schnaare, R.L., Cohl, G., Moench, T., Doncel, G., Watson, K., Buckheit, R.W., Jr., Lewis, M., Mauck, C., Callahan, M., Douville, K. and Romano, J.W. - AIDS Res. Hu. Retrov. 21: 11-19. 2005.

Microbicide

Synthesis and antiviral properties of 1-{[2-(phenoxy)ethoxy]methyl}uracil derivatives.

Novikov, M.S., Ozerov, A.A., Orlova, J.A., Buckheit, R.W., Jr. - Chemistry of Heterocyclic Compounds. 5:726-731. 2005.

Antiviral

Potent inhibition of HIV-1 entry by (s4dU)35.

Horvath, A., Tokes, S., Hartman, T., Watson, K., Turpin, J.A., Buckheit, R.W., Jr., Sebesteyen, Z., Szollosi, J., Benko, I., Bardos, T.J., Dunn, J.A., Toth, F.D., Fesus, L. and Aradi, J. - Virology. 334:214-223. 2005.

Antiviral

Synthesis and anti-HIV activity of new alkenyldiarylmethane (ADAM) non-nucleoside reverse transcriptase inhibitors (NNRTIs) incorporating benzoxazolone and benzisoxazole rings.

Deng, B.L., Cullen, M.D., Zhou, Z., Hartman, T.L., Buckheit, R.W., Jr., Pannecouque, C., DeClercq, E., Fanwick, P.E. and Cushman, M. - J.Med.Chem. 48:6140-6155. 2005.

Antiviral

Isolation and characterization of griffithsin, a novel HIV-inactivating protein from the red algae Griffithsia sp.

Mori, T., O’Keefe, B.R., Sowder III, R.C., Bringans, S., Gardella, R., Berg, S., Cochran, P., Turpin, J.A., Buckheit, R.W., Jr., McMahon, J.B. and Boyd, M.R. - J. Biol. Chemistry. 280:9345-9353. 2005.

An unusual “senseless” 2’,5’-oligoribonucleotide with potent anti-HIV activity.

Aboul-Fadi, T., Agrawal, V.K., Buckheit, R.W., Jr. and Broom, A.D. - Nucleosides and Nucleotides 23:545-554. 2004.

Antiviral

Optimization of unique uncharged thioesters as inhibitors of HIV replication.

Srivastava, P., Hara, T., Fattah, R.J., Schito, M., Hartman, T., Buckheit, R.W., Jr., Turpin, J.A., Inman, J.K., and Appella, E. - Bioorg.Med.Chem. 12: 6437-6450. 2004.

Expression, purification, and characterization of recombinant cyanovirin-N for vaginal anti-HIV microbicide development.

Colleluori, D.M., Tien, D., Kang, F., Pagliei, T., Kuss, R., McCormick, T., Watson, K., McFadden, K., Chaiken, I., Buckheit, R.W., Jr. and Romano, J.W. - Protein Expression and Purification. 39:229-236. 2004.

Antiviral

Synthesis and antiviral activity of 2-(alkylthio)-5-[2-(aryloxy)ethyl]-6-methylpyrimidine-4(3H)-ones.

Novikov M.S., Sim O.G., Ozerov A.A., Buckheit R.W. - Bulletin of Volgograd Scientific Centre of Russian Academy of Medical Sciences. 2:30-31. 2004.

Antiviral

Synthesis and anti-HIV-1 activity of 1-(benzyloxymethyl)-5-(arylamino)uracil derivatives methylated in side chain.

Ozerov A.A., Novikov M.S., Gnatjuk V.P., Lobachev A.A., Buckheit R.W. - Bulletin of Volgograd Scientific Centre of Russian Academy of Medical Sciences.1:26-28. 2004.

Antiviral

Understanding HIV resistance, fitness, replication capacity and compensation: targeting viral fitness as a therapeutic strategy. In press.

Buckheit, R.W., Jr. - Expert Opin. Investig. Drugs 13: 933-958. 2004.

Synthesis and anti-HIV-1 activity of 2-[[2-(3,5-dimethylphenoxy)ethyl]thio]pyrimidin-4(3H)-ones.

Novikov, M.S., Ozerov, A.A., Sim, O.G. and Buckheit, R.W., Jr. - Chemistry of Heterocyclic Compounds. 40:37-42. 2004.

Antiviral activity of hop constituents against a series of DNA and RNA viruses.

Buckwold, V.E., Wilson, R.J.H., Nalca, A., Beer, B., Voss, T.G., Turpin, J.A., Buckheit, R.W., Jr., Wei, J., Wenzel-Mathers, M., Walton, E., Pallansch, M., Ward, P., Wells, J., Chuvala, L., Sloane, S., Paulman, R., Russell, J., Hartman,T. and Ptak, R. - Antiviral Research. 61:57-62. 2004.

Antiviral